Pandafarmer said:
It matters to me. I may not devote deep study or statistical analysis to my card gaming, but I still build decks to win. If a first-turn win exists, anywhere in the metagame, I have substantially less interest in the game. Even if I never find the combo, even if it takes cards I'm unlikely to see: it exists, and that lessens the enjoyment of the game for me.
It's rather like how I find it hard to enjoy chess these days. I can accept that there are people who are better than me at the game: I don't devote much study to it, nor do I have any great innate talent, so that is to be expected. What I have trouble with is that there are computers that are better than me at the game. And not just computers, but slow computers. Even if I don't play against computers, I still know they're out there, and that just ruins my enjoyment.