My main concern with Rebels is what are they going to do with 3 Jedi (well one in training)? You don't hear any mention of any Jedi's surviving the Clone Wars in the OT. Are they all going to be killed off? Go into hiding? You'd think that if Kanan lives he'd be involved in the Rebellion some how and Luke would have known/heard about him. Same for Ezra and Asoka.
I hope they don't make the canon wonky.
Also, I feel like the killed the Inquisitor off too quickly. I wanted to know more about his back story and how there came to be Inquisitors. He might still be alive though...
The only ones that really talk as if there are no Jedi left are the Imperial Officers in the OT. They act as though Vader was the last one left alive despite Yoda and Obi-Wan being very much alive. Sure, he hunted down the Jedi as a group but that doesn't mean some exiles still didn't exist. They'd likely have given up their previous ways and spent a lot of their time on the Outer Rim planets to escape the Empire and Vader.
If Kanan & friends go into hiding for one reason or another, the canon is the same. "That boy is our last hope." Obi-Wan says this, not necessarily meaning Luke's the last Jedi but the only one that can actually confront Vader and not immediately be killed because he is Vader's son and they know Vader can still redeem himself.