Let's assume that Nyarlathotep will feature as an AO in the game, and that hopefully he's the last AO released so that he can in some way connect and use aspects of every other AO.
Looking ahead then (and maybe as a nudge-nudge wink-wink to FFG) what ways could they make Nyarlathotep truly unique and epic, to the point where he uses a near completely different system to the usual mechanics if nessesary. Unlikely I guess, but you never know.
To start more simply, I'd like to see at least a dozen different mysteries for him, each representing a different guise.