Having taken about a year and a half out of GM-ing due to various reasons, I've desided to start up a new game involving 2 close mates and my gf.

The opening lines will be something like this:

"The first thing you are aware of is the throbbing pain in the back of your head as, gradually, you start to regain conciousness. Around you you can hear the rattling of chains, laboured breathing and the occasional moan. You open your eyes are greeted by more darkness and blurred shapes. As you adjust to the gloom you can make out 5 other figures in various states of decay chained up against the wall. You try to move and the high pitched rattling of cold steel chains assaults your ear-drums as you realise you aren't going anywhere. A faint moan comes from the centre of the room and you force your eyes to focus on the figure strapped to a pinth. Two large glass containers hang on iron stands to either side if the man, 1 empty, 1 filled with a bright green liquid, with tubes puncturing each arm. To your horror the empty jar starts to fill with blood as the green fluid level starts to go down. There is a brief moment of silence followed by a loud scream that echos around the chamber. You turn your head to avoid the grizzly sight only to see a green fluid filled jar and a tube leading to your arm........."

What do you think guys?

Sounds interesting. Where do you plan to go from there? For my campaigns, I always plan at least a session in advance. I've been running the various "fan scenarios" from 2e and just changing the skills and monsters to 3e. Here are the download links: dl.dropbox.com/u/167876/WFRP%20COMPLETE%20SCENARIO%20LIST%20with%20download%20links.pdf

That's certainly a dramatic call to action for your players! I like it as an opening. I echo Emirikol. What do you plan to take this? Is it going to be a major campaign, or just a scenario, or...?

I like it, mechanically it reminds me a bit of a segueway I used after an apparent TPK in a 2e campaign. All of the players spent a fate point after going up against a foe they shouldn't have. Their bodies were left for dead and found by Clan Moulder. Campaign resumed to the players escaping and finding out a few years had passed (and one of the players harbored a dark secret from the experimentation).

I have to say, your description is leagues better than whatever I hashed together for the event.