The Netflix show Stranger Things has some pretty strong Lovecraftian themes, especially the second season with gates to other realms, monsters emerging from those gates, etc. I was thinking Arkham Horror could easily be adapted for Stranger Things using Strange Aeons or even have Fantasy Flight release an officially licensed version with the consent of Netflix.
Map locations could include:
The Byers Home
The Wheeler Home
The Henderson Home
The Sinclair Home
Hawkins Police Station
Hawkins Middle School
Hawkins National Laboratory
The Quarry
Bradley's Big Buy
Benny's Burgers
The Palace Arcade
Mirkwood
Player Characters could include:
Will
Mike
Eleven
Lucas
Dustin
Jonathan
Nancy
Steve
Joyce
Hopper
Max
Bob
Owens
Monsters could include:
Demogorgons
Demodogs
Brenner
Government spooks
The GOO would of course be the Mind Flayer