I want to see some madmen attempt (and beat) this challenge
Expansions: All (Base, Forsaken Lore, Mountains of Madness, Strange Remnants, Under the Pyramids, Signs of Carcossa, The Dreamlands)
Ancient One: Atlach-Nacha
Prelude: Twin Blasphemies of the Black Goat
Investigators: 4
Reference Cards: Original (you can use Revised if you are truly mad)
Special Rules: Modify the Mythos Deck so that the 1st card you draw is "Render of the Veils"
We stumbled upon this setup by accident and it was truly terrifying. The only difference was we had the Otherworldly Dreams Prelude.
We managed to solve half of the first mystery, and then the world became one giant spider web.