So... let's say you want to create a first adventure for DH. You have new players with PCs newly drafted into the Inquisitor's service... How would you begin the investigation?
I mean, the Inquisitors aren't cops who investigate every single disturbance. They and their acolytes sit in some base... and what now? In what way do they learn that on some world, something is amiss? What kind of thing must happen for them to be notified?
In this kind of setting, getting the PCs involved seems a bit harder than, say, in a Call of Cthulhu scenario...