I tried finding if this question had been asked but didn't see anything straight away. I also can't find this answer in the rule book or the FAQ. Take, for example, Wyrm Pogram: Icebreaker.

It says I can pay 1 credit to weaken ice by -1 and I can pay 1 credit to give +1 strength.

My question is, can I pay more credits to stack the benefit? Can I pay 3 credits for +3 strength and 2 credits for -2 ice?

As many times as you wish to and can afford to pay the cost, you can use the ability.

Also, since you're looking at Wyrm, it's worth noting that in order for it to hand out the -1 Strength Wyrm must itself equal the Strength of the ICE. It's not immediately obvious from just looking at the card, but it makes sense when you remember Icebreakers need to equal or beat an ICE's Strength in order to interact with it. The FAQ makes this explicit.

So, the point of Wyrm is generally not to break the ice itself, but rather to support a fixed-STR breaker like mimic, Yog, Darwin, or Atman by burning the ice to a level the other breaker can break efficiently.

So, the point of Wyrm is generally not to break the ice itself, but rather to support a fixed-STR breaker like mimic, Yog, Darwin, or Atman by burning the ice to a level the other breaker can break efficiently.

Or to accelerate your Parasite if you have cash to spare/not enough Datasucker tokens.