Is it posible to run a Adepta Sororitas Game using Dark Heresy?

I ask bacause some freinds of mine are interested in restarting a game I was runing a few years ago using 40K Rogue Trader edition and Necromunder as a bace for my rule set, They'ed like to re-start the game but using a more complex and Canon rule set.

Back when we palyed the characters where a Adepta Sororitas (Seriphim) squad and the Psyker Twin Sister of the Squad leader, who was an Adepta Sororitas Novice herself before her Psyker nature was discovered.

DH is the WH40K RP set of rules. My first reaction was to use Necromunda as a Hive setting for my adepts in the Calixis sector, and Im sure people are using it as a Necromunda themed campaign. Most of the creatures from both Rogue Trader and Necromunda have been given stats in the latest books. It is exactly what your looking for.

Yes you can play an all AS game if you wish. If you want it to be completely by the books, you'll need to pick up the Inquisitors Handbook as it's the book that details the AS career as well as the powers of faith.

The adepta Sororitas is the career best suited for a whole group of them - it branches into the orders dialoguos, hospitaler and militant, so you have your social/healing, your social/knowledgy and your fighty one.

All the Gals are Order Militant, even the Psyker before her cruse on the Black Ship was trained in the Order Militant, tjhough in thr original campain their was an order Hosplier NPC and a Fedils/Tech who was almost good enough to qualify as a Templar and just young enough to be concidered for late Sub-Adualt entry in to the Order

Not even sure I understand a reasoning for the question. Its a Career in the game so obviously the possibility is there. Though you might want to create a few alternate backgrounds and what not to bring a bit variety to the band, unless you plan on starting them all off a 1000+ XP.

Well I was woundering If I could recreate the characters from the old Campain with little hassles, just bacause their is a Career path dosent mean it will suit my needs, but it looks like it will, and if I want to re do the NPC's I can do so.

At the moment just using the Core Book I'm going to try runing a game using orignal Characters over the easter beake just so we can learn the system, so whrn it comes time to re do the Nuns it will be easer.