My group started this adventure this last Sunday. We have an ongoing campaign ( http://www.obsidianportal.com/campaigns/emperor-preserve ) and we just made the switch to DH2. Everyone kept their same character they've been playing but we reworked them all from the DH2 ground up in the session before this last one. I modified Seeds a bit to meld with our story arc and it seems to have fit quite nicely. Many of my comments echo some already made.
My first impression was I liked the wide-open structure of the adventure - it offers a lot of possibilities with different potential levels of complexity.
As our session approached I got a bit nervous about this same "wide-openness" - definitely puts more on the GM to be ready for whichever direction your players choose. I went with the adventure's recommended structure, which I won't go into because my players might read this. My anxiousness was the combination of an adventure with a lot of moving parts and a new system I hadn't played with yet.
Once my players arrived I could stop over-thinking and just tell the story. Didn't keep up with the Subtlety, Disposition & Personality trifecta that well, particularly the latter two; that's going to need some work...but it'll come. I like the new narrative tools.
I very much like the Building Combat Encounters section in DH2 - though wish its scheme wasn't opaque so I could easily use it with NPCs I'd created.
That's a start...I'll post more about it later.