Ok, so I've not been shy about not being happy with my first read-through of the combat rules. However, combat isn't the heart of roleplaying... characters are. So, I did a little experiment with character creation.
Lilly Ryan, Rogue Psyker
Homeworld: Hive World, Background: Outcast, Role: Mystic
WS 35 BS 30 S 30 T 30 Ag 40 I 45 P 35 WP 45 F 45 If 30
Skills: Acrobatics +0, Deceive +0, Evade +0, Intimidate +0, Navigate +0, Psyniscience +0, Stealth +0, Survival +0
Talents and Traits: Evasive, Weapon Training (chain, SP)
Corruption: 12
Psy Rating 1, Psy Powers: Telepathic Link, Influence, Warp Perception
Lilly is a favorite 40K roleplay character who I made before Dark Heresy came out... a hive ganger wyrd. It's interesting to me that I am able to create her under these rules without much problem at all. That speaks of a level of flexibility when it comes to character concepts. At the same time, the lack of options when it comes to starting skills will mean that any other Outcast character will have the same basic skills, except only what they buy from their Role. Advances are expensive, so there isn't a lot of flexibility there.
One question that Lilly brings up is, do Rogue Psykers start with Malignancies? The rules for Malignancies say that a character each time their corruption increases by 10, but it doesn't mention starting Corruption.
One other thing I noticed in creating a character is the lack of Imperial World as a homeworld option. That seems a rather glaring omission to me.