---Update---
Well, after much thought and contemplation, I've developed a bit of plot for this benign heresy. Let me know what you think... any suggestions would definitely be appreciated!
___________________________________
I. Set out - The acolytes set out from Scintilla, after meeting with Inquisitor Tyburn Graves. He has sent them to Iocanthos, to investigate some possible warp-activities at the site of a newly-raised cathedral. This segment follows the procedure from Illumination, found in the main DH manual.
II. Trouble in the Warp - During the middle of warp-transit, the acolytes awake suddenly to the sound of warning klaxons blaring throughout the ship. The Brazen Sky is under attack! Daemons have managed to get inside the geller shield after an unknown malfunction, and the heroes must fight their way to the bridge to force the ship into realspace. During this period, the ship suffers severe damage to the generator.
III. Crash - The stricken Brazen Sky shudders back into realspace, inside an unknown system. The surviving astropath simply mutters to himself that "the beacon has gone out" and "madness surrounds us! The warp is all-round!", and cannot be roused further. The acolytes, should they look outwards, would see a roiling warp-storm, maddening to behold, surrounding the small sun and system that orbits it. There is not much time for contemplation, though, as the ship is being pulled into the nearest planetoid's gravitational well. The players have enough time to detect an Imperial distress signal eminating from the planet's green and blue moon, and with some luck, manage to crash land near the beacon.
IV. A Situation Develops - The acolytes discover the beacon is buried in the remains of an Adeptus Mechanicum outpost on the moon, apparently named "Kanto", an otherwise unknown location. This Adeptus outpost is positioned high on the top of an isolated mountain, overlooking what is apparently a city in the distance. A few "monsters" will be in the genatorium of the outpost, but once cleared out, emergency power can be restored.
In the cogitator's data arrays, the record of what had happened can at least partially found. The majority of the facility had been decimated by Genetorium Construct MW-2, a hybrid crossing human DNA with that of a indiginous creature to the system, one with extremely high control over its powerful psyker abilities. Several weeks ago, Construct MW-2's void-shielded contaiment cell had suddenly malfunctioned, and it was let loose. It anniahlated the outpost and nearly all of its residents, save two lower-level tech-adepts, who managed to avoid detection and recorded the aftermath of the outbreak.
V. The Mission Becomes Clear - The final archived records warn any visiting Imperial rescue crews to be wary of the natural life forms of the world; most, if not all seem to be in touch with the warp on a base level, but since the outbreak of MW-2, they have become far more easily agitated and outright hostile to humans. Many exhibit strange abilities, and some, if not daemons, are certainly close to them. This has been attributed to some sort of subliminal control by MW-2, as well as the sudden warp-storm that has enshrouded a large portion of the system, preventing normal communication.
The two acolytes have since set out from the ruined facility, brave the lethal indigens in land surrounding the outpost in order to make the long trek to the closest human settlement, Sapphron. There, they hope to gain support from the local people, and purge MW-2 from the planet, hopefully dispelling the warp-storm.
This obviously reeks of tech-heresy. The mingleling of the sacred form of humans with that of xenos? The acolytes know what must be done...

