I am soon going to start a new DH campaign focusing on a new radical faction within the Calixian Conclave: Nephthytes. Basically, a group of Inquisitors who took the cue from Erya Nephthys and are trying to become immortal by any means necessary to better fight the forces that threaten the Imperium.
Now, the characters themselves will be working for a radical himself, a former tech-priest who harbors ideas similar to the Logicians and, to a lesser extend, the Phaenonites, although he hates the latter with a bitter passion.
Tech-heresy, especially in regards to gene-abominations and violations of the human form divine will be a pretty big point here and at one point I want to introduce the Dark Eldar and their ways of fleshcrafting.
The Acolytes and their master have no idea about the secretive " Ordo Revenum" (the wannabe-immortals) at first and will only learn about the conspiracy much later…but, apart from these pointers, I have no structure for the campaign yet….and would be grateful for any further suggestions and ideas.