Many fantastic ideas concerning the potential use or purpose of the dread Tyrant Star, if I may be so inclined to do so I'd like to add my two cents into the pot.
For my purpose, Calixis as it stands is a place where the fate of the Imperium (and indeed the Materium itself) is to be decided. Komus's true purpose is that of a "Final Gateway" that connects the Warp and Real Space, should this gate ever be opened it can then never be closed again and all things will become one (essentially the Eye of the Abyss x100000).
Feeling the gate's presence the Ruinous Gods race to see who will cross over the gate and claim ultimate dominion over both realms and desperately call upon their followers to open the gate in his name (thus allowing them to exist in both worlds and rule both). Coinsiding with all this is an increased activity in the sector's known Cults as well as the arrival of a new Cult (a Khornite based cult that is woefully missing from the books) and named Champions of each god and a Greater Daemon to aid them.
All the while as the acolytes struggle to defeat and contain them they are secreted aided by...Baphomeal and the Brotherhood who (ironicly) don't want the gate opened but events are moving in strange ways and each Ruinous God has his own plan for ultimate conquest....
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