1) A BS test vs a character that is running with Hard Target talent suffer a -20 or -40 malus (-20 for Hard Target + -20 for running)?

2) Blind Fighting is just for colse to close combat or also attacks with ranged weapons?

The modifiers stack, shooting a Running Hard Target is an Ardous (-40) test.

Blind Fighting helps with both Ranged and Melee attacks when your vision is impaired.