this was a topic awhile back (wondering how treasure cards work, how they go into deck, etc). courtesy of Hastur360 on CGDB:
"Treasure:
A player is permitted to add a treasure card to his deck if both of the following conditions are met:
1. The players has discovered the specific treasure card he wishes to use through game text in a previous scenario using the same group of heroes he is currently playing with.
2. The specific treasure card belongs to a treasure set that is listed in the setup instructions for the scenario currently being played. The treasure set icon appears in place of a sphere icon on the treasure cards, and can also be used to identify which scenario it can be discovered in.
Any treasure card that meets the above conditions can be added to a player's deck during the setup of a scenario. No more than 1 copy of any treasure card, by title, can be added to a player's deck. Treasure cards added to the deck do not count towards that deck's 50 card minimum."