I'd be more interested in the idea of a game set in a sector that the Imperium is starting to crusade into and you get to play as teh various minor Xenos species within. No Eldar, Tau or Orks.
Kroot, Hrud, Tarrelian Dog-soldiers, Umbra (for those that want to play a floating magic 8-ball), Nekuli, Niccassar, Demiurg, and all the other creatures that just get a vague nod of the head occasionally. THAT'S what I want to see!