Good point on characters or supports with struggle icons getting a boost from this. Shaping the icon struggle should be a more viable strategy given greater diversity in Conspiracy cards. There seems to be more focus on the Combat and Terror struggles in most decks, so Combing the Archives will create headaches for players who don't include some struggle icons in their decks.
Dr. Bartlett certainly gets a boost as well, but the card that will really be coming into its own is Ol' Lazy Eyes. Very powerful in combination with Into the Woods or Combing the Archives (but also Endless Investigation, and possibly others).
Also, could be some interesting possibilities with Conspiracy Theorist, although the difficult is keeping him alive against the plentiful destruction effects floating around right now.