Having given the 'Description' section a more thorough read, I can see at least 2 significant changes. Firstly, the graphics are a lot clearer. Some of the print on the old cards was very tiny. They have done away with 'colour coding' as well. The old 'Agendas' were very blue and the 'Nodes' very green. It made identification of the 'types' very simple, but a quick flash of a card would also give a clue to the Runner. Yes, it looks like FFG have done their usual high standard graphically.
The second is a whole new concept. That of different 'styles' of Corporations and Runners in the form of 'Identities'. I can only speculate as to what impact this might have on the play. Will these be like 'Factions' allowing only their kinds of cards in their respective decks, or specific 'abilities' usable only by specific 'Identities? The former would open up the 'deck building' element, but the latter could lead to more difficulty in balencing the 2 sides.
I shall be monitoring this games progress very closely as FFG have a hard act to follow, but first impressions look favourable. We need a bit more to go on, but knowing FFG, they get so far ahead of themselves in announcements, that it seems ages before anything really concrete comes out. This may help with the excitment, but if expectations are allowed to go on too long, apathy can set in or the final project struggles to fullfill the hype. Cheers!