So far on iPad gen1 fully updated iOS I have been dealing with the following issues:
1. The game keeps losing my inapp purchase. I have to restore it constantly. If I am not in a wifi area I am screwed and have to wait.
2. When playing azathoth (which I keep getting limited to by above) I have noticed that the myths cards follow the same pattern. Doom+3, doom +1 and monster, doom+2 twice, doom+3. I understand trying to make the game a challenge, but making a set path and removing randomness is more annoying than challenging. Plus thus limits me to barely 6 rounds before I lose. With that timeframe, trophies are useless, as you will rarely have time to get enough to buy elder signs, and makes wasting a round in the store for anything else a guaranteed game ender.
3. Someone mentioned that the dice are now skewed, and I have noticed this. If this is true, that would be annoying as well. Losing do to randomness is a pain, but part of the game. Losing because the game is programmed to make you lose makes the game crap.