After looking at the two most recently published APs in the updated DeckBuilder I realized I really need to pay more attention to spoilers if I want to avoid new cards spoiling my new fun deck ideas.
First in Conspiracies of Chaos we have:
Beneath the Mire
[Neutral] Conspiracies of Chaos F60 / Illustrator: Regis Moulun
[Event] -
Cost : 2
Game Text: Play on your opponent's turn after all players have committed their characters. Action: Each player who has committed at least one character to 3 or more stories this phase sacrifices all committed characters.
Flavor text: "This should fix everything..." - Vaughn
What a nasty showstopper for a heedless early rush! 
And then we get a card in the Curse of the Jade Emperor that makes me truly unhappy:
Palpable Unhappiness
[Hastur] Curse of the Jade Emperor F35 / Illustrator: Cristi Balanescu
[Event] -
Cost : 1
Game Text: Action: Choose a story. All characters committed to that story have their skill lowered to 0.
Flavor text: The air was heavy with fear and sadness. The breeze stirred up eddies of terror.
If I interpret this effect correctly, no amount of skill-boosting will help the committed characters in any way. Nobody can succeed at this story this turn!
The arrival of these cards has wrecked my most promising deck ideas - I really love to hate these cards! 
Looks like I'll have to resort to playing mono Cthulhu after all... 
