For less page flipping, I will quote the relevant sections from the rulebook
Stun (Full Action) [p. 191]
When unarmed or armed with a melee weapon, you can strike to Stun rather than attempt to land a killing blow. Whilst any character may attempt this action, only characters with the Takedown talent stand a good chance of succeeding. Striking to Stun is resoved in a similar way to making a standard attack. Test Weapon Skill. If you don't have Takedown, take a -20 to the test. On a success, roll 1D10 and add your Strength Bonus. Your opponent rolls 1D10 and adds his toughness bonus +1 per Armour Point protecting his head. If your roll is equal to or higher,your opponent is Stunned for a number of rounds equal to the difference between the rolls and gains one level of Fatigue.
If I understand it correctly, this Attack is insanely useful when unarmed, as the Attack automatically targets the head (normally the least armoured area of your enemy), if there is Armour it doesn't count double as usual, and you also have a comparably high chance of dealing fatigue damage (and of course Stun) compared to a normal Unarmed Attack that has a very slim chance of actually damaging of even fatiguing anyone who is only slightly armoured.
Takedown (Talent) [p.122]
As a Half Action you may declare that you are attempting to Takedown an opponent before testing Weapon Skill. If you hit and do at least one point of Damage, this damage is ignored and your opponent must make a Toughness test or be stunned for one round.
First thing: This does in no way mention the removal of the Malus to Stun Actions. If it's not too late FFG, please add that to the next version of the Dark Heresy Core Rulebook.
As I understand it, the Takedown Talent gives you a Bonus on the Stun Attack as well as a new Action called Takedown that works differently.
Because several parts of the rulebook were a bit confusing (the Becoming Stunned section [p. 200] not mentioning the Stun Attack for example), I just wanted to make sure I understood this correctly.
If I do, I'm definitely looking forward to buy Takedown for my Feral World Guardsman, who can then proceed to Stun ► Grapple ► Fatigue KO every heavily armoured/armed Enemy he comes across while nekkid.