When Interrogator-Chaplain Boreas and his squad go aspirant hunting in the Angels of Darkness novel he breaks the neck of one of the three "winners" of the initial tests because he chickend out when the apothecary had to go poking about in his tummy with his gear. Well, he didnt kill him because he chickend out, but because he'd seen to much of the chapter and the astartes, and this was still on the kids home planet.
So let's break it down.
First, the girl in question have to make it far enough in the initial trials, be it gladiatorial combat or whatever.
Second, the initial apothecary tests, and here she's busted. What would hapen to her then? Well' depending on chapter it could be anything from serf, mindcleansed and made into a servitor (for use in the apothecarium or librarium perhaps?) or just, as in the example stated above, killed and burried and honored in a seecret cave with other failed aspirants.