I just got me to wondering: what would be the ultimate conflict in Arkham Horror, the most terrifying concatenation of fathomless evil that would send any mortal misfortunate enough to gaze upon its hideous countenance spiralling into the uttermost darkness of using "Cyclopean" and "batrachian" in the same sentence? Having come up with this little thought, I had another - who the heck could actually beat it?
So, the two-horned challenge begins. To start, concoct if you will the hardest setup you can imagine for an Arkham Horror game. Any legal combination of GOO, Herald, expansions and optional decks is permitted, but if you want to use an expansion's board, monsters, Mythos cards or OW cards you must use all four of those elements.
Then, to play against this scenario, devise a team of Investigators. This team can be made up of characters from any set, with only two rules. First, Personal Stories must be used in the game. Second, to keep the game limits consistent you must select four Investigators plus one additional Investigator for each expansion board after the first in your scenario.
I'll whomp my way through the Wiki and see what I can come up with, but I think Abhoth plus Mum and Dad on AH+Innsmouth would be pretty crazy. Yibb-Tstll and Ghroth doesn't sound like the easiest combo either - effective Doom Track of 9, a Clue cap, any Mystic drawn forces you to either take a hit and risk a Doom token or lose the ability to seal, and if you try taking it to Final Battle all your Clues get eaten.