I received the board expansions for Arkham for Christmas which I had not previously had and some friends and I have been familiarizing ourselves with them.
I wanted to check with the boards and see how you treat the expansion items at your tables.
So far we have not been using GOO's or Investigators from one board expansion with another. This does not seem to limiting though, and as host I'm thinking now that the new investigators & GOO's have been "showcased" in a few games we should just start pulling from a common pot of all investigators and all GOO's regardless of which boards are in play.
I have also been segregating all spells, common items and unique items and only shuffling them in when their relevant sets are in play. I believe this is correct.
Lastly, we have been using relationships in all games and using personal stories in most games. It seems that the personal stories tend to be distractions from the primary goals, I notice that personal stories games run a bit longer and the doom track trends higher. I didn't know if there had been a preference of leaving those items out or keeping them in.
No guardians used yet, however we have endured defeat at the hands of Hastur and the KiY herald twice now. Need to gear up for some payback there this weekend.