I bring you all into my hypothetical situation.
(Somewhere in Nevada) GM Adam is running a game of Ascension (remember, Adam, Ascension) for Inquisitor Isaac and his Throne Agents. Inquisitor Isaac decides it's time to recruit some Acolytes to do some dirty work for him, so he spends the XP and takes the advance.
(Meanwhile, somewhere in Delaware) Derek is about to start running a game of Dark Heresy (remember, Derek, Dark Heresy) for a group of Acolytes.
(Back in Nevada) GM Adam has stayed in contact with his old college buddy Derek. During one of their semi-regular conversations, Derek happens to mention that he is about to start running a game of Dark Heresy. GM Adam has a great idea; why doesn't Derek run the cell as if they were under Inquisitor Isaac? The Acolytes would receive mission orders from the Inquisitor to do something he is either incapable or does not want to do.In essence, the following happens (as an example).
Inquisitor Isaac decides that he needs his Acolyte team to frame the planetary governor for some heresy so that Isaac can step in, condemn him, and take control of the production facilities there. So Inquisitor Isaac sends word to his Acolytes. Meanwhile, GM Adam tells GM Derek that the Inquisitor of the Acolytes has an assignment for them, and the two of them discuss what this will entail, what obstacles the Acolytes will face, what other variables are present, etc. GM Derek then runs the mission with his players and then one of the players submits a report to their Inquisitor when it is complete. The Inquisitor, satisfied or otherwise with his Acolytes, acts accordingly....
You may now step out of my hypothetical. Thoughts?