So far my favorite ship design items are Planet Bound for Millenia and Auxiliary Plasma Banks. With Planet Bound, you really get so many awesome goodies cheap. You get the modified drive for space cost only, you get one bit of Archeaotech, for the trade off of -1d5-1 Hull Integrity (-1d5 for LC and Crusiers). You also get +10 Man near a planet. The modified drive gives you a speed +1.
Auxiliary Plasma Banks give you more power, and cost a little space. They might blow up on a critical hit, but it is worth the risk.
Anyone else have favorites, and why?