On for the fiction and canon-buffs. Every other Black Library book has a wacky Inquisition scheme to save the Imperium from Chaos or the Tyranids. This normally so horrifies the associated Guard/Marine character POV as it involves the wastage of entire worlds to test. I'm thinking here of things like the Genestealer disease vector in "Deathwatch" graphic novel or controlling Tyranids in "Warrior Brood", controlling Chaos with the Shadowlight etc. But when have these plans ever achieved the results they were meant to? Each one seems to be made of pure fail.
Now this isnt the Inquisition reacting to Heretics plans- Eisonhorn and Ravenor are successful at uncovering evil plots and thwarting them. But they dont sit around devising a master scheme to Save the Imperium.
The closest I've ever seen of such an Inquisitorial master plan succeeding was Kryptmans scorced earth strategy to turn the Tyranid Hive fleet into Orc-space, but even then it suggests that once the 'Nids are finsihed digesting, they'll be stronger and greener than ever.
So, has any Inqusition scheme ever worked?
SJE