I have Descent Journey in the Dark and the Well of Darkness expansion. I would like to try sea of blood next. Do I have to have any of the other expansion sets to play this one?

No. The other sets will all work with SoB, but you don't need them.

Nope! I have vanilla Descent and Sea of Blood and it seems to be working quite well. The overlord will have fewer minion choices in some scenarios. I've been thinking about picking up Tomb of Ice to get feats for the heroes.

Unless you have a strong reason, I'd suggest playing Road to Legend before Sea of Blood. RtL is reasonably balanced right out of the box, while Sea of Blood can be massively broken in favor of the OL, depending on your starting avatar and plot.

That's weird! I picked up Sea of Blood because RTL was supposed to be biased in favor of the overlord. Something about free lieutenants giving him an unfair early boost.

leprejuan said:

RtL has now been through 2 editions of FAQing and is quite balanced though it takes skilled players to manage that balance. It is after all an Advanced Campaign. Not for powderpuff players.
Frankly, having analysed and played both games (SoB camapigns not yet into silver though) I'd say that the RtL Lt mechanics are much, much better/fairer than the SoB ones.

SoB only just came out before the most recent FAQ so although there is stuff for SoB in the current FAQ the game had hardly been played so there are many, many issues that have not been addressed by the FAQ and probably still many issues that haven't even been found yet. How many campaign reports have covered an entire SoB campaign up to and including the final battle? - I don't think I've read a single one! While I am sure that some people have completed a campaign and been through a SoB final battle, far too few groups have done it for the issues to come out. And there are issues, big ones - or at least, there certainly were with RtL and appear to be if you can read through ahead for SoB. FFG simply doesn't appear to use playtesters (if they do any playtesting it seems to be with a bunch of people who play far too nice and thus blindly drift past the nasty, tricky or messy problems without even noticing) and if you think about it, such long, complex, multivaried games as the advanced campaigns would require stupidly huge amounts of playtesting to actually test many things!

In summary, RtL is a settled, developed, relatively mature offering, maybe a v1.51 whereas SoB is barely a v1.01 and in software terms should probably be rated about v0.9 except that it has already been released.