Has anyone updated the actual plague? It originally said Initial Damage 1Dex and 1Str, Secondary Damage 1d3 Con.

If not here's what I'm initially thinking (I have a high xp group).

A failed Resilience check (difficulty varies based on level of campaign) means Wound Threshold reduced by number of failures, Strain Threshold reduced by number of threats. Despair reduces Brawn and/or Agility characteristic by 1.

I know folks have done the Tempest spice, and will be looking around for that next.

BTW, I think the Tempest Feud link in the Resources thread that's pinned no longer works?

I do not know much about the source material, but you should probably have the WT reduction be 1+failure. A wash is technically a failure, but in this case nothing would happen and would be equivalent to a success.