(without things like Call Ancient One or a game with less than 4 investigators)
Let me give you a wild example so you could see how impossible it is:
A 4-player game. One of the investigators is Joe Diamond. He reaches the final battle with the Fight and Grapple and even Martial Arts (I did say wild example). He also has a blessing and 10 clues. Every roll other than 1 and 2 is a success. He also has a Shotgun.
So, he maxes out his fight to 5, which 6 thanks to Fight. Adding Martial Arts that's 10 dice but wait! Quachil's -3 renders it 7 dice. So he spends 10 clues. Remember- every clue is worth 3 dice. So, 37 clues, Grapple, Blessing and Shotgun. Awesome, right?
Wrong. Let's do some math: Each die has a 66% chance of rolling a success. That's an average of 24 successes. But wait! we forgot the Shotgun. Each die has a 16.66% chance of producing an extra success. With 37 dice, that's 6 extra successes on average. Let's sum it up: 30 successes. Which is... wait for it...
7 doom tokens removed (with 2 leftover successes).
All of that, all of this craziness, for only a little more than half of Quachil's doom track.
But wait! there are more investigators! Sure, but they probably don't pack what Joe is packing and they will produce very few successes, probably. And an investigator is devoured every round.
Now let's get back to reality: No one will have that combination of skills and items I just mentioned. As you see, even if someone, even Joe, will have them, victory is still questionable.
So back to the title: Is it possible?

