I think the major thing with the mandolorian is it feels how we imagine people would live in this universe; like it is in no rush to get from plot point A to B, it was happy to slowly wander through to the A plot after establishing the status quo of the mandolorian, spent a whole episode giving the Mandolorian reason to care about the little one while building up the side character of Griff a little more as a guy who "has seen some stuff and has a lot of life experience, but is happy living the simple life.", spends half an episode building up to the inevitable "when will the mandolorian decide to change the status quo?" before crack. It all happens and we feel it is a sangicent moment that will impact on every minute of his life after that, something that is built up over another 3 episodes. It's very kind of remisent of A New Hope in that it starts with intense action, then establishes the status quo up so we understand what normality means to the character so that when things do change, we feel that change. Same with Hoth; we get a sense of what life is like there before the Empire arrives e.c.t. It's a slightly low key nostalgia, aside from having a extreme 6 second close up to blue milk.
And that's what biomarkers is; if it's inferred that midicholorians is the force, it's certainly not in any movie or source material I've seen. Biomarkers detected in the body and tested for usually aren't the core symptom of what the scientists are actually looking for; they are usually a bioproduct of some other biomechanical purpose that produced that particular protein/ketone as a bi-product. Mitochondria likewise once existed as a completely independent species of bacteria that through some unknown process became integrated within the cells as a mutually exclusive relationship, mitochondria produce the power, we feed it. I imagine the relationship with midcholorians, which I imagine Luca's more or less ripped off; came to be in some peudo science fashion. The force/fate is strong in an individual? More folks gather and some bright sod figured out how to detect them as a good biomarker to measure potential. It's really simple as that.
Interesting sidenote; Mitochondria can only be inherited by the maternal side of the family, so midicholorians obviously don't work in the same way otherwise Leia would've won the lottery and left Luke high and dry, so it's inferred that exactly what motivates these little fellas isn't governed by what we understand. That being said, Luca's is a story writer not a scientist so I would expect him to take the name and basic inference, nothing more. In the same way that Jedi are peusdo samurai with hints of Buddhism and Taoism, duality and what not lashed onto the standard fantasy epic trope of defeating an evil wizard.
Wrong word