I think it would be cool is if FFG made or allowed someone to make an Arkham Horror program that was basically just a map of the board that could be used in online play between two or more people that have the game. I know they knocked down a full online game version, but this would force someone to have bought the game.
So it would be a screen representation of the board, and the only thing it would do is tell you the investigatorsAO used, tell you which items/spells are drawn, and which monsters appear. Once person uses their own cards for locations/mythos (voice chat would be necessary) and either that person uses cards for everyone else, or each player can keep track of their own if they have the game. None of the monsters, items, or investigators would have any information in the program, it could just keep track of money, stamina, and sanity. You tell it everything that goes on. So it would be just like it is in real life, as long as one person has the actual game, a group could play. It would just allow people to play that normally wouldn't, and would definitely be worthless to pirate since it won't work without the cards (although I guess you could just go to the wiki, but anyone could do that now and make copies of anything they want).
I think it would be cool and easier than skyping the way some of you tried it. And it could be very basic, as long as it lets two people see where things are at on the board. Do you think they would even allow something like this?