Had this one come up tonight: if my opponent has a creature with a Biomatrix Backup and I play Destroy Them All, what happens if I target their creature and the Backup? Three possibilities:
1. I'm the active player, so I make timing choices. I can target the Backup first, destroy it and then destroy the creature.
2. The destruction must resolve in the order listed on the card, so the creature has to go first triggering the Backup ( and forcing me to Target a different Upgrade, if one exists).
3. All the destruction happens simultaneously, so the Backup will trigger, but the Backup will be destroyed and no other Upgrade needs to be targeted.
What's the right answer to this?