After a recent conversation with my GM relating to this, most characters are drastically changed after an Ascension transition package. Most notably in insanity and corruption, now my question came down to this:
1) How does this work for characters such as those with the From Beyond trait as per the Radical's Handbook? How does such a character gain the insanity when by definition the character is immune to it? Likewise, how do Untouchables, being immune to most things which cause Corruption (with a capital C, as opposed to corruption from mundane, non-warp based sources such as radiation, virus, etc.) factor in?
2) For background packages such as the Moritat as they gift Traits, how do these relate to Ascension? Are these wiped out?
I'd prefer a response from FFG on the issue, as it seems if you allow these packages an extreme amount of power-gaming is available, but on the other hand it restricts what characters can be actually used in the Ascension system after progressing through eight ranks. Given, I found it odd that the packages often gifted insanity and corruption when a character who has staved off these things for eight ranks might just end up insane becoming an Interrogator or something akin, but that's another issue entirely.