Ive finished a mini fantasy campaign, now Im starting a gothic campaign, originally plannned for Leagues of Gothic Horror. I think that ubiquity its a fine system.
But the narrative dice system has me in love.
The campaign would be based in the turnoil of Buenos aires at the end of XIX century. and using the supused net of jesuist tunnels from the colony times.
No interested in lovecraftian horror. Im not saying that Lovecraft isnt a good author, but they tales arent my cup of tea, im more a romnaticism guy, with Lefanu, Dickens, Becquer, and the like as isnpiration.
Now, how you handle things like mysticism? I think that wierd science is covered in in the CRB