In my area, the pre-nerf-Phantom-like arc-dodging capability of PS10 Nym, combined with the desire to limit him to throwing only his 2 bomb dice against you before you shot and not add 2-6 more from his weapons, had already lead to a flood of Quickdraw/Backdraft/Vader/Chiraneau/Dengar with VI/Adaptability.
With the release of Harpoon Missiles, many of those already-popular ships have gained triple-U-boat levels of alpha strike punch, with the added bonus that they do it before most pilots ever printed can shoot back. They're no longer mostly a hard counter to Nym. They're also amazing at removing 25-33% of your opponent's ships from the board before they've done anything.
Essentially, it feels like there are only three effective values for PS right now: 11, 10, and "lower". Put a pilot on the board who's a 7 or a 9 and you've wasted half a dozen squad points. Give him Juke or PtL and you waste even more. Listbuilding looks really restricted in the post-Guns meta. If a ship doesn't have at least 9 health, at least 8 PS + EPT, or a counterattack, you can't rely on it even shooting once. The Imperial 4-mini-ace archetype looks dead -- after the first round of combat, you'll have the same number of ships as your opponent, except yours have less health and shoot last. Swarms, which were the practical solution in previous waves to lists that can reliably focus-fire down key individual targets, look to be suicide this time around due to all that AoE harpoon damage. What's left? Flat pancakes, joining what you can't beat, and...?