So. went to the wiki and saw the FAQ they had about C-3po and Flight Instructor, and would presume the same precedent with the following interaction:
Defender guesses 0 with C-3po, rolls an (eyeball), and thus adds an (evade) result (so, adds a green die with an evade on it).
Attacker now modifies defense dice, so spends target lock with R4-B11 to make the defender reroll the die with the evade result.
Now the Defender would modify the dice (spend evade, spend focus, etc.)
Edited by HanScottFirst