The rules state that -60 is the greatest negative modifier you can face and +60 is the greatest positive. They are unclear on two points 1. whether or not skill raises and the talented talent are calculated into the +60 limit and whether or not the max is -60+60 = 0 or -60 +120 = +60. In any event the book states that plotting a course without the astronomicron is a hellish -60 task. This got me thiking.
Dark Age of Technology
Warpsbane Hull +10% Navigation Rolls
Two Assistant Navigators +20% Navigation (+1 level of success of successful see page 232).
Exceptional Charts +20%
Ancient Almanac Astrae Dvinitus (i.e. Nav Comp) +10%
= +60%
Going beyond charted Space
Without charts might want to be on a cruiser for the +5% bonus from a ship masters bridge. Add in a Talented Navigator (this is an exploration mission after all) and you got -5%.
And in the present timeline, if you can't get good charts a Runecaster is a great idea (though it's a xeno artifact).
Conclusion: The Astronomicon makes ships much cheaper to build (warpsbane hulls not mandatory) and cuts the required number of navigators. The real question is, if you offset the penalty for not being able to see the astronomicron (or nearly offset it) do you use the standard navigation rules instead of requiring that the navigator make the roll?