20 minutes into the match, block off range 1 from each player's side of the board (whole board gets smaller by 8" or so). 40 minutes in, block off range 1 from the sides. 60 minutes in, range 1 again from all sides. Now you have a smaller area to run that's filled with asteroids. If your ship is in the blocked off area when time to block it happens you have 1 move to get back on the board, then regular rules for edge of the board apply - ship destroyed.
Running is part of the game, your opponent has to be able to catch you. I think it only gets detrimental when people also slow play. You know what running looks like, engage or don't. I've run in tournaments before, but my dials were also down long before my opponents. Think of it like the final 2 minutes in basketball.