No spoilers.
Playing through the first campaign, Roland as solo hero. Got to the Devourer below. Start with 2 mental trauma, Draw 5, discard 2. Still have elder sign amulet in my had to boost sanity. Decide I would rather draw 2 cards and move in order to keep the quest moving.
First encounter card drawn: Rotting Remains. "That's okay," I say to myself, "These remains can't be ALL bad." Testing 3 to a 3, I commit the Elder Sign Amulet for 2 willpower, bringing me up to 5 to a 3.
Now, chaos bag. I know I don't have to pass this, but I need at least a -4 and I'll survive. Reach in and guess what.
Yep, the Deep One token. -5. I lose 3 sanity and go insane. First turn, total wipe. Thanks chaos bag!
What makes this worse is I was playing on "easy" mode to get the hang of it. Still, probably some of the most fun I've had in a card game.