This one's bound to surface sooner rather than later, so it would be nice to clear it up: if Biggs is within range 1 of the ship that you have locked can you choose to use a weapon that requires a target lock to fire and thus ignore Bigg's effect? At first glance it would seem so, because you cannot use that weapon against Biggs due to lack of target lock. However the timing chart for performing the attack contains following points during the "Declare target" step:
(...)
ii.
Attacker chooses weapon
iii.
Declare target of the attack
iv.
Pay cost to perform the attack (if applicable)
(...)
So it basically boils down to this: does "declare target of the attack" already take into account that you have to pay the cost thus making Biggs a non-legit target for that attack or does Biggs still block the attack in question? I believe the former is true, since the cards for weapons with that requirement typically contain the keyword "Attack (target lock)", limiting the list of potential targets only to the ships you have locked.
Edited by Lightrock