I'd love for that list to work, but good luck getting those TLs versus the dominating PS7+ lists.
Can't say I've ever had problems acquiring Target Locks on ships. What you no longer have is the easymode "just focus and see if they come into arc" approach. You have to work for your targets. You'll have to setup multiple overlapping arcs after acquiring your targets. But it still hits like a truck and Manaroo gives you some flexibility on target switching in the combat phase.