As I understood from what's been revealed so far the campaign foresees up to three fleets per side fighting individually and then culminating in one big 1.500 point showdown,
In a 2 player game managing 3 fleets shouldn't be very hard. In fact, one won't have to squabble over who gets to fly this or that admiral, at least.
However, the final match might be logistically impossible in a 2 player game. Say the imperial player has at least one ISD in each 500 point fleet. The final battle would require that he own 3 ISDs to play (and heaven knows how many gladiators and so on).
I hope they have a system for 2 players without access to a gazillion copies of the same ship.