As a big Game of Thrones fan I'm actually quite excited about this (though I wish they used artwork rather than show stills--would look way more classy).
But I am worried that the limited number of Houses (that most people care about) might limit this games expansion long before the devs are out of interesting ideas and mechanisms. After all, howerver cool a House Redwyne or House Royce faction could be...I don't think the average consumer would care about them. Now, they could solve this by doing sub-factions of the main Houses but then we could have two or three versions of the same characters running around...
Then again, this looks like it may be geared more towards the casual market ala GoT: The Card Game (the TV-art edition) that was a stripped down, mass-market focused product more for the Target, Barns and Noble set.