OK, i'm a huge fan of the films of Hayao Miyazaki (since my wife got me into it via her childhood favourite My Neighbour Totoro ).
I'm assuming from what i've read of Anima, that it has the feel of films like Totoro, Princess Mononoko, Spirited Away, Howls Moving Castle , etc.
But is it pure fantasy or does it contain rules to model 'modern' and 'sci-fi / sci-fantasy' sources like Porco Rosso, The Castle of Cagliostro, Laputa , etc. or even into western sci-fantasy of a similar type like Philip Reeve's Mortal Engines ?
I must say i VERY much like what i see of Anima, but i'd be more interested in the sci-fi / sci-fantasy game settings if i were to invest in the rules...
above all if you want to have a high technology level in your game, because you will need to modify the existant setting.