Game with all expansions is massive.
I guess most campaigns were designed and tested only with core game and that expansion, so adding so much could easily destroy the balance.
I think that there are three things that mostly change the balance:
1. Plot decks.
2. Rumors.
3. H&M collections
So Plot decks just add power to Overlord. You may argue that fortune tokens might be good for heroes too, but it's always OL choice to give them to heroes in the first place. And you could alwasys take Trystaine deck and use only base card, which doesn't give anything to heroes. Personally I like the idea, cause there are times when you as OL can't win a quest, and ability to gain threat tokens just add secondary objective (like gold for heroes, though gold is much more usefull).
There are different kind of Rumors (with or without quest). First type helps the Overlord, second type can help both. But too many side quests lengthen the main campaign.
H&M collection adds a lot to both sides, that's true, But monster quality is really good and you can only use 4 heroes and ALL monsters from these packs. So this helps OL too.
With this in mind I want to discuss some things
1. Do you use plot decks? Why?
2. Do you use rumores? Why?
3. Do you use all H&M packs? Why?
4. Are there any overpowered/underpowered heroes/monsters/plot decks/Ol cards? Which one?