We used to do 150 point games when we started but it ends up being a bit lopsided after the first turn whoever hit the hardest tends to maintain that advantage the rest of the game.
At 100 there isn't enough firepower to wipe out half the other guys list in a turn and you can have aces or numbers but not both.
The game really is well balanced at 100, having that limitation forces you to think about what works well and what you can live without.
Bigger games can be a blast but for regular games 100 just works.