The push-happy Blood Angels librarian in my current campaign has finally triggered the insta-death option from the peril of the warp charts mid-mission. My method of GM'ing is more focused on the everyone having a good time so I am not extremely strict in following the rules. Due to the player being attached to the character and his tendencies of making the missions more interesting (I believe the daemon prince summoned tracker is nearing 15) I decided to go with an alternative to simply having him make a new character. On top of burning a fate point he was given 3d10 corruption and insanity, 1d10 permanent damage to two random characteristics, and a random mutation from the gift of the dark gods from BC. In addition his character suffers the effects of lost to the warp and will automatically trigger the perils of the warp chart in any event perils are triggered. Overall the character gained 23 corruption, 12 insanity to gain the first stage of the primarchs curse, 4 damage to FEL, 2 damage to WS, gained the warp-touched mutation (Entropy), and played a large part in the failure of the mission. I do plan to have the Assassinorum and Inquisition be heavily involved in the future due the effect of lost to the warp as sabotaging a very high level Ecclesiarch would tend to do bring them into play.
tldr;
Throughout all this I was wondering what other alternatives has the community applied to their respective games or is RAW strictly followed in your campaigns with the psyker being irrevocably destroyed.