I miss the days when Jedi were just normal people with monastic training, instead of being special midichlorian babies. I really hope midichlorians get retconned out with the new Star Wars movies. Maybe make it so that you're not born with them so much as they just hang out with people or something and people who are more likely to possess monkly attributes are more likely to accumulate them, I don't know.
These days live on at my gaming table.
Our reconciliation for midichlorians (not that we needed one, but it was fun to come up with) is that regular or powerful Force Use attracts them. Thus they can provide a useful indicator, if you know what to look for.